Research output per year
Research output per year
Personal profile
About
My research involves the development of bioinformatic tools to help pharmacists, health professionals and the public better understand complex genomics data, from data processing and analysis pipelines to dashboards for easy visualization. I am also mining and analyzing large metabolomics databases to better understand drug treatment and response mechanisms.
I am also a frequent collaborator with scientists at Butler University and around the country. My contributions have included the processing, analysis, and visualization of different types of 'omics data. Research projects have included the profiling of 'omics data in leukemia, to understand disease progression and treatment response; analysis of gene splicing and polyadenylation patterns to identify treatment mechanisms in pancreatic cancer; and epidemiological analysis to understand why some breast cancer patients do not receive chemotherapy after it is recommended by their doctor.
Related documents
Education/Academic qualification
Biostatistics, Postdoctoral Fellowship, MD Anderson Cancer Center
… → 2018
Chemical Engineering, Ph.D., Massachusetts Institute of Technology
… → 2015
Chemical Engineering Practice, M.S., Massachusetts Institute of Technology
… → 2011
B.S., Purdue University, West Lafayette
… → 2009
Disciplines
- Medicine and Health Sciences
- Pharmacy and Pharmaceutical Sciences
Research output
- 30 Article
-
Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy
Ganan-Gomez, I., Yang, H., Ma, F., Montalban-Bravo, G., Thongon, N., Marchica, V., Richard-Carpentier, G., Chien, K., Manyam, G., Wang, F., Alfonso, A., Chen, S., Class, C., Kanagal-Shamanna, R., Ingram, J. P., Ogoti, Y., Rose, A., Loghavi, S., Lockyer, P. & Cambo, B. & 18 others, , Mar 3 2022, In: Scholarship and Professional Work – COPHS. 28Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Activation of gene expression by detergent-like protein domains
Broyles, B. K., Gutierrez, A. T., Maris, T. P., Coil, D. A., Wagner, T. M., Wang, X., Kihara, D., Class, C. & Erkine, A. M., Sep 24 2021, In: Scholarship and Professional Work – COPHS. 24Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Hematopoiesis under telomere attrition at the single-cell resolution
Thongon, N., Ma, F., Santoni, A., Marchesini, M., Fiorini, E., Rose, A., Adema, V., Ganan-Gomez, I., Groarke, E. M., Gutierrez-Rodrigues, F., Chen, S., Lockyer, P., Schneider, S., Bueso-Ramos, C., Montalban-Bravo, G., Class, C., Soltysiak, K. A., Pellegrini, M., Sahin, E. & Bertuch, A. A. & 5 others, , Nov 25 2021, In: Scholarship and Professional Work – COPHS. 12Research output: Contribution to journal › Article › peer-review
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Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cance
Evans, K. W., Yuca, E., Scott, S. S., Zhao, M., Paez Arango, N., Cruz Pico, C. X., Saridogan, T., Shariati, M., Class, C., Bristow, C. A., Vellano, C. P., Zheng, X., Gonzalez-Angulo, A. M., Su, X., Tapia, C., Chen, K., Akcakanat, A., Lim, B., Tripathy, D. & Yap, T. A. & 6 others, , Nov 1 2021, In: Scholarship and Professional Work – COPHS. 21Research output: Contribution to journal › Article › peer-review
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PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma
Giuliani, V., Miller, M. A., Liu, C.-Y., Hartono, S. R., Class, C., Bristow, C. A., Suzuki, E., Sanz, L. A., Gao, G., Gay, J. P., Feng, N., Rose, J. L., Tomihara, H., Daniele, J. R., Peoples, M. D., Bardenhagen, J. P., Geck Do, M. K., Chang, Q. E., Vangamudi, B. & Vellano, C. & 18 others, , Jul 30 2021, In: Scholarship and Professional Work – COPHS. 12Research output: Contribution to journal › Article › peer-review
Open AccessFile