A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients

Elaine G. Cox; Chad A. Knoderer; Aimee Jennings; John W. Brown; Mark D. Rodefeld; Scott G. Walker; Mark W. Turrentine

doi:10.1093/jpids/pis066

A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients

Elaine G. Cox, Chad A. Knoderer, Aimee Jennings, John W. Brown, Mark D. Rodefeld, Scott G. Walker, Mark W. Turrentine

Research output: Contribution to journal › Article › peer-review

Abstract

We conducted a randomized, controlled clinical trial to determine whether a difference in catheter-associated blood stream infection (CABSI) incidence existed between children who underwent cardiac surgery and had a central venous catheter impregnated with minocycline and rifampin versus those who had a conventional, nonimpregnated catheter after cardiac surgery. Due to a lower number of infections than expected, the study was terminated early. Among 288 evaluable patients, the rates of CABSI and line-related complications were similar between the 2 groups.

Original language	American English
Journal	Scholarship and Professional Work – COPHS
Volume	2
Issue number	1
DOIs	https://doi.org/10.1093/jpids/pis066
State	Published - Jan 1 2013

Keywords

cardiovascular patients
catheter related infectious events
pediatrics
randomized trials

Disciplines

Pediatrics
Pharmacy and Pharmaceutical Sciences

Access to Document

10.1093/jpids/pis066License: Unspecified

A Randomized Controlled Trial of Catheter-Related Infectious EveFinal published version, 501 KBLicense: Unspecified

Cite this

Cox, E. G., Knoderer, C. A., Jennings, A., Brown, J. W., Rodefeld, M. D., Walker, S. G., & Turrentine, M. W. (2013). A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients. Scholarship and Professional Work – COPHS, 2(1). https://doi.org/10.1093/jpids/pis066

A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients. / Cox, Elaine G.; Knoderer, Chad A.; Jennings, Aimee et al.
In: Scholarship and Professional Work – COPHS, Vol. 2, No. 1, 01.01.2013.

Research output: Contribution to journal › Article › peer-review

Cox, EG, Knoderer, CA, Jennings, A, Brown, JW, Rodefeld, MD, Walker, SG & Turrentine, MW 2013, 'A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients', Scholarship and Professional Work – COPHS, vol. 2, no. 1. https://doi.org/10.1093/jpids/pis066

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abstract = " We conducted a randomized, controlled clinical trial to determine whether a difference in catheter-associated blood stream infection (CABSI) incidence existed between children who underwent cardiac surgery and had a central venous catheter impregnated with minocycline and rifampin versus those who had a conventional, nonimpregnated catheter after cardiac surgery. Due to a lower number of infections than expected, the study was terminated early. Among 288 evaluable patients, the rates of CABSI and line-related complications were similar between the 2 groups.",

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A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients

Abstract

Keywords

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