Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma

Virginia Giuliani; Alessandro Carugo; Meredith Miller; Lionel Sanz; Chiu-Yi Liu; Christopher A Bristow; Erika Suzuki; Caleb A Class; Stella R. Hartono; Guang Gao; Ningping Feng; Bhavatarini Vangamudi; Joseph R Marszalek; Jeffrey Kovacs; Maria Emilia Di Francesco; Frederic Chedin; Philip Jones; Giulio Draetta; Timothy Heffernan

doi:10.1158/1538-7445.AM2019-277

Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma

Virginia Giuliani, Alessandro Carugo, Meredith Miller, Lionel Sanz, Chiu-Yi Liu, Christopher A Bristow, Erika Suzuki, Caleb A Class, Stella R. Hartono, Guang Gao, Ningping Feng, Bhavatarini Vangamudi, Joseph R Marszalek, Jeffrey Kovacs, Maria Emilia Di Francesco, Frederic Chedin, Philip Jones, Giulio Draetta, Timothy Heffernan

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Cancer Research
Volume	79
DOIs	https://doi.org/10.1158/1538-7445.AM2019-277
State	Published - Jul 1 2019

Disciplines

Biology
Oncology

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Giuliani, V., Carugo, A., Miller, M., Sanz, L., Liu, C.-Y., Bristow, C. A., Suzuki, E., Class, C. A., Hartono, S. R., Gao, G., Feng, N., Vangamudi, B., Marszalek, J. R., Kovacs, J., Di Francesco, M. E., Chedin, F., Jones, P., Draetta, G., & Heffernan, T. (2019). Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma. Cancer Research, 79. https://doi.org/10.1158/1538-7445.AM2019-277

Giuliani, V, Carugo, A, Miller, M, Sanz, L, Liu, C-Y, Bristow, CA, Suzuki, E, Class, CA, Hartono, SR, Gao, G, Feng, N, Vangamudi, B, Marszalek, JR, Kovacs, J, Di Francesco, ME, Chedin, F, Jones, P, Draetta, G & Heffernan, T 2019, 'Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma', Cancer Research, vol. 79. https://doi.org/10.1158/1538-7445.AM2019-277

@article{148465627ca84451ba274f7b4eb198de,

title = "Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma",

author = "Virginia Giuliani and Alessandro Carugo and Meredith Miller and Lionel Sanz and Chiu-Yi Liu and Bristow, \{Christopher A\} and Erika Suzuki and Class, \{Caleb A\} and Hartono, \{Stella R.\} and Guang Gao and Ningping Feng and Bhavatarini Vangamudi and Marszalek, \{Joseph R\} and Jeffrey Kovacs and \{Di Francesco\}, \{Maria Emilia\} and Frederic Chedin and Philip Jones and Giulio Draetta and Timothy Heffernan",

note = "Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA With limited therapeutic options, poor overall 5-year survival rates, and increasing incidence, pancreas cancer is estimated to become the second leading cause of cancer deaths by 2030.",

year = "2019",

month = jul,

day = "1",

doi = "10.1158/1538-7445.AM2019-277",

language = "American English",

volume = "79",

journal = "Cancer Research",

}

TY - JOUR

T1 - Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma

AU - Giuliani, Virginia

AU - Carugo, Alessandro

AU - Miller, Meredith

AU - Sanz, Lionel

AU - Liu, Chiu-Yi

AU - Bristow, Christopher A

AU - Suzuki, Erika

AU - Class, Caleb A

AU - Hartono, Stella R.

AU - Gao, Guang

AU - Feng, Ningping

AU - Vangamudi, Bhavatarini

AU - Marszalek, Joseph R

AU - Kovacs, Jeffrey

AU - Di Francesco, Maria Emilia

AU - Chedin, Frederic

AU - Jones, Philip

AU - Draetta, Giulio

AU - Heffernan, Timothy

N1 - Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA With limited therapeutic options, poor overall 5-year survival rates, and increasing incidence, pancreas cancer is estimated to become the second leading cause of cancer deaths by 2030.

PY - 2019/7/1

Y1 - 2019/7/1

UR - https://cancerres.aacrjournals.org/content/79/13_Supplement/277

U2 - 10.1158/1538-7445.AM2019-277

DO - 10.1158/1538-7445.AM2019-277

M3 - Article

VL - 79

JO - Cancer Research

JF - Cancer Research

ER -

Abstract 277: Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma

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