Abstract
The purpose of this retrospective chart review was to determine the correlation between full weight-based enoxaparin use and the frequency of anti-Xa concentrations within the defined therapeutic range; to ascertain if anti-Xa monitoring is being appropriately ordered in relation to the timing of enoxaparin dose (after 3 consistent therapeutic doses and 3-5 hours post-dose); to establish if the evidence-based recommended dose adjustment protocol that was studied in the pediatric population was utilized; and if this yielded anti-Xa concentrations within the target range (0.6 – 1.1 IU/mL) for an adult population. The data may suggest a lack of correlation between BMI and whether or not the anti-Xa concentration is within the therapeutic range. Further prospective studies are needed to confirm this finding, and to determine the utility of the available dose adjustment nomogram.
| Original language | American English |
|---|---|
| Journal | Scholarship and Professional Work – COPHS |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 2013 |
Keywords
- anti-Xa concentrations
- enoxaparin
Disciplines
- Pharmacy and Pharmaceutical Sciences
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