CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade

Limo Chen; Lixia Diao; Yongbin Yang; Xiaohui Yi; B. Leticia Rodriguez; Yanli Li; Yanli Li; Pamela A. Villalobos; Tina Cascone; Xi Liu; Lin Tan; Philip L. Lorenzi; Anfei Huang; Qiang Zhao; Di Peng; Jared J. Fradette; David H. Peng; Christin Ungewiss; Jonathon Roybal; Pan Tong; Junna Oba; Ferdinandos Skoulidis; Weiyi Peng; Brett W. Carter; Youhong Fan; Caleb A. Class; Jingfen Zhu; Jaime Rodriguez-Canales; Masanori Kawakami; Lauren Averett Byers; Scott E. Woodman; Vassiliki A. Papadimitrakopoulou; Ethan Dmitrovsky; Jing Wang; Stephen E. Ullrich; Ignacio I. Wistuba; John V. Heymach; F. Xiao Feng Qin; F. Xiao Feng Qin; Don L. Gibbons

doi:10.1158/2159-8290.CD-17-1033

CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade

Limo Chen
, Lixia Diao
, Yongbin Yang
, Xiaohui Yi
, B. Leticia Rodriguez
, Yanli Li
, Yanli Li
, Pamela A. Villalobos
, Tina Cascone
, Xi Liu
, Lin Tan
, Philip L. Lorenzi
, Anfei Huang
, Qiang Zhao
, Di Peng
, Jared J. Fradette
, David H. Peng
, Christin Ungewiss
, Jonathon Roybal
, Pan Tong

Junna Oba, Ferdinandos Skoulidis, Weiyi Peng, Brett W. Carter, Youhong Fan, Caleb A. Class, Jingfen Zhu, Jaime Rodriguez-Canales, Masanori Kawakami, Lauren Averett Byers, Scott E. Woodman, Vassiliki A. Papadimitrakopoulou, Ethan Dmitrovsky, Jing Wang, Stephen E. Ullrich, Ignacio I. Wistuba, John V. Heymach, F. Xiao Feng Qin, F. Xiao Feng Qin, Don L. Gibbons

University of Texas MD Anderson Cancer Center
Shanghai First People's Hospital, Shanghai, Shanghai, China.
Shanghai Jiao Tong University
Peking Union Medical College
Sun Yat-sen University
MedImmune

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Cancer Discovery
Volume	8
Issue number	9
DOIs	https://doi.org/10.1158/2159-8290.CD-17-1033
State	Published - Jan 1 2018

Disciplines

Medicine and Health Sciences
Oncology

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Chen, L., Diao, L., Yang, Y., Yi, X., Rodriguez, B. L., Li, Y., Li, Y., Villalobos, P. A., Cascone, T., Liu, X., Tan, L., Lorenzi, P. L., Huang, A., Zhao, Q., Peng, D., Fradette, J. J., Peng, D. H., Ungewiss, C., Roybal, J., ... Gibbons, D. L. (2018). CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade. Cancer Discovery, 8(9). https://doi.org/10.1158/2159-8290.CD-17-1033

Chen, L, Diao, L, Yang, Y, Yi, X, Rodriguez, BL, Li, Y, Li, Y, Villalobos, PA, Cascone, T, Liu, X, Tan, L, Lorenzi, PL, Huang, A, Zhao, Q, Peng, D, Fradette, JJ, Peng, DH, Ungewiss, C, Roybal, J, Tong, P, Oba, J, Skoulidis, F, Peng, W, Carter, BW, Fan, Y, Class, CA, Zhu, J, Rodriguez-Canales, J, Kawakami, M, Byers, LA, Woodman, SE, Papadimitrakopoulou, VA, Dmitrovsky, E, Wang, J, Ullrich, SE, Wistuba, II, Heymach, JV, Qin, FXF, Qin, FXF & Gibbons, DL 2018, 'CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade', Cancer Discovery, vol. 8, no. 9. https://doi.org/10.1158/2159-8290.CD-17-1033

@article{adf00f5464f747599eb01e5f6d7465ba,

title = "CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade",

author = "Limo Chen and Lixia Diao and Yongbin Yang and Xiaohui Yi and Rodriguez, \{B. Leticia\} and Yanli Li and Yanli Li and Villalobos, \{Pamela A.\} and Tina Cascone and Xi Liu and Lin Tan and Lorenzi, \{Philip L.\} and Anfei Huang and Qiang Zhao and Di Peng and Fradette, \{Jared J.\} and Peng, \{David H.\} and Christin Ungewiss and Jonathon Roybal and Pan Tong and Junna Oba and Ferdinandos Skoulidis and Weiyi Peng and Carter, \{Brett W.\} and Youhong Fan and Class, \{Caleb A.\} and Jingfen Zhu and Jaime Rodriguez-Canales and Masanori Kawakami and Byers, \{Lauren Averett\} and Woodman, \{Scott E.\} and Papadimitrakopoulou, \{Vassiliki A.\} and Ethan Dmitrovsky and Jing Wang and Ullrich, \{Stephen E.\} and Wistuba, \{Ignacio I.\} and Heymach, \{John V.\} and Qin, \{F. Xiao Feng\} and Qin, \{F. Xiao Feng\} and Gibbons, \{Don L.\}",

year = "2018",

month = jan,

day = "1",

doi = "10.1158/2159-8290.CD-17-1033",

language = "American English",

volume = "8",

journal = "Cancer Discovery",

number = "9",

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TY - JOUR

T1 - CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade

AU - Chen, Limo

AU - Diao, Lixia

AU - Yang, Yongbin

AU - Yi, Xiaohui

AU - Rodriguez, B. Leticia

AU - Li, Yanli

AU - Villalobos, Pamela A.

AU - Cascone, Tina

AU - Liu, Xi

AU - Tan, Lin

AU - Lorenzi, Philip L.

AU - Huang, Anfei

AU - Zhao, Qiang

AU - Peng, Di

AU - Fradette, Jared J.

AU - Peng, David H.

AU - Ungewiss, Christin

AU - Roybal, Jonathon

AU - Tong, Pan

AU - Oba, Junna

AU - Skoulidis, Ferdinandos

AU - Peng, Weiyi

AU - Carter, Brett W.

AU - Fan, Youhong

AU - Class, Caleb A.

AU - Zhu, Jingfen

AU - Rodriguez-Canales, Jaime

AU - Kawakami, Masanori

AU - Byers, Lauren Averett

AU - Woodman, Scott E.

AU - Papadimitrakopoulou, Vassiliki A.

AU - Dmitrovsky, Ethan

AU - Wang, Jing

AU - Ullrich, Stephen E.

AU - Wistuba, Ignacio I.

AU - Heymach, John V.

AU - Qin, F. Xiao Feng

AU - Gibbons, Don L.

PY - 2018/1/1

Y1 - 2018/1/1

UR - https://cancerdiscovery.aacrjournals.org/content/candisc/early/2018/07/14/2159-8290.CD-17-1033.full.pdf

U2 - 10.1158/2159-8290.CD-17-1033

DO - 10.1158/2159-8290.CD-17-1033

M3 - Article

VL - 8

JO - Cancer Discovery

JF - Cancer Discovery

IS - 9

ER -

CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade

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