Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Rashmi Kanagal-Shamanna; Guillermo Montalban-Bravo; Caleb Class; Koji Sasaki; Christopher B. Benton; Kelly Soltysiak; Elias Jabbour; Tapan M. Kadia; Carlos E. Bueso-Ramos; Keyur P. Patel; Mark Routbort; Irene Ganan-Gomez; Yue Wei; Gautam M. Borthakur; Farhad Ravandi; Kim-Anh Do; L. Jeffrey Medeiros; Hagop M. Kantarjian; Guillermo Garcia-Manero

doi:10.1182/BLOOD-2019-130545

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Rashmi Kanagal-Shamanna
, Guillermo Montalban-Bravo
, Caleb Class
, Koji Sasaki
, Christopher B. Benton
, Kelly Soltysiak
, Elias Jabbour
, Tapan M. Kadia
, Carlos E. Bueso-Ramos
, Keyur P. Patel
, Mark Routbort
, Irene Ganan-Gomez
, Yue Wei
, Gautam M. Borthakur
, Farhad Ravandi
, Kim-Anh Do
, L. Jeffrey Medeiros
, Hagop M. Kantarjian
, Guillermo Garcia-Manero

University of Texas MD Anderson Cancer Center

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Blood
Volume	134
DOIs	https://doi.org/10.1182/BLOOD-2019-130545
State	Published - Nov 13 2019

Disciplines

Medicine and Health Sciences
Oncology

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Kanagal-Shamanna, R., Montalban-Bravo, G., Class, C., Sasaki, K., Benton, C. B., Soltysiak, K., Jabbour, E., Kadia, T. M., Bueso-Ramos, C. E., Patel, K. P., Routbort, M., Ganan-Gomez, I., Wei, Y., Borthakur, G. M., Ravandi, F., Do, K.-A., Medeiros, L. J., Kantarjian, H. M., & Garcia-Manero, G. (2019). Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia. Blood, 134. https://doi.org/10.1182/BLOOD-2019-130545

Kanagal-Shamanna, R, Montalban-Bravo, G, Class, C, Sasaki, K, Benton, CB, Soltysiak, K, Jabbour, E, Kadia, TM, Bueso-Ramos, CE, Patel, KP, Routbort, M, Ganan-Gomez, I, Wei, Y, Borthakur, GM, Ravandi, F, Do, K-A, Medeiros, LJ, Kantarjian, HM & Garcia-Manero, G 2019, 'Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia', Blood, vol. 134. https://doi.org/10.1182/BLOOD-2019-130545

@article{c24e527e0e0647d197a0c691ffd25683,

title = "Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia",

author = "Rashmi Kanagal-Shamanna and Guillermo Montalban-Bravo and Caleb Class and Koji Sasaki and Benton, \{Christopher B.\} and Kelly Soltysiak and Elias Jabbour and Kadia, \{Tapan M.\} and Bueso-Ramos, \{Carlos E.\} and Patel, \{Keyur P.\} and Mark Routbort and Irene Ganan-Gomez and Yue Wei and Borthakur, \{Gautam M.\} and Farhad Ravandi and Kim-Anh Do and Medeiros, \{L. Jeffrey\} and Kantarjian, \{Hagop M.\} and Guillermo Garcia-Manero",

note = "INTRODUCTIONTP53 mutated myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) have a poor outcome. TP53 mutations occur throughout the coding region",

year = "2019",

month = nov,

day = "13",

doi = "10.1182/BLOOD-2019-130545",

language = "American English",

volume = "134",

journal = "Blood",

}

TY - JOUR

T1 - Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

AU - Kanagal-Shamanna, Rashmi

AU - Montalban-Bravo, Guillermo

AU - Class, Caleb

AU - Sasaki, Koji

AU - Benton, Christopher B.

AU - Soltysiak, Kelly

AU - Jabbour, Elias

AU - Kadia, Tapan M.

AU - Bueso-Ramos, Carlos E.

AU - Patel, Keyur P.

AU - Routbort, Mark

AU - Ganan-Gomez, Irene

AU - Wei, Yue

AU - Borthakur, Gautam M.

AU - Ravandi, Farhad

AU - Do, Kim-Anh

AU - Medeiros, L. Jeffrey

AU - Kantarjian, Hagop M.

AU - Garcia-Manero, Guillermo

N1 - INTRODUCTIONTP53 mutated myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) have a poor outcome. TP53 mutations occur throughout the coding region

PY - 2019/11/13

Y1 - 2019/11/13

UR - https://ashpublications.org/blood/article/134/Supplement_1/1719/427719/Evolutionary-Action-EA-Score-of-TP53-Mutations

U2 - 10.1182/BLOOD-2019-130545

DO - 10.1182/BLOOD-2019-130545

M3 - Article

VL - 134

JO - Blood

JF - Blood

ER -

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

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