Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes

Guillermo Montalban-Bravo; Rashmi Kanagal-Shamanna; Christopher B. Benton; Caleb Class; Kelly S. Chien; Koji Sasaki; Kiran Naqvi; Yesid Alvarado; Tapan M. Kadia; Farhad Ravandi; Jorge E. Cortes; Naval G. Daver; Koichi Takahashi; Courtney D. DiNardo; Elias Jabbour; Gautam M. Borthakur; Naveen Pemmaraju; Marina Y Konopleva; Sherry A. Pierce; Carlos E. Bueso-Ramos; Michael Andreeff; Keyur P. Patel; Hagop M. Kantarjian; Guillermo Garcia-Manero

doi:10.1182/BLOOD-2019-124978

Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes

Guillermo Montalban-Bravo
, Rashmi Kanagal-Shamanna
, Christopher B. Benton
, Caleb Class
, Kelly S. Chien
, Koji Sasaki
, Kiran Naqvi
, Yesid Alvarado
, Tapan M. Kadia
, Farhad Ravandi
, Jorge E. Cortes
, Naval G. Daver
, Koichi Takahashi
, Courtney D. DiNardo
, Elias Jabbour
, Gautam M. Borthakur
, Naveen Pemmaraju
, Marina Y Konopleva
, Sherry A. Pierce
, Carlos E. Bueso-Ramos

Michael Andreeff, Keyur P. Patel, Hagop M. Kantarjian, Guillermo Garcia-Manero

University of Texas MD Anderson Cancer Center

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Blood
Volume	134
DOIs	https://doi.org/10.1182/BLOOD-2019-124978
State	Published - Nov 13 2019

Disciplines

Medicine and Health Sciences
Oncology
Internal Medicine

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Montalban-Bravo, G., Kanagal-Shamanna, R., Benton, C. B., Class, C., Chien, K. S., Sasaki, K., Naqvi, K., Alvarado, Y., Kadia, T. M., Ravandi, F., Cortes, J. E., Daver, N. G., Takahashi, K., DiNardo, C. D., Jabbour, E., Borthakur, G. M., Pemmaraju, N., Konopleva, M. Y., Pierce, S. A., ... Garcia-Manero, G. (2019). Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes. Blood, 134. https://doi.org/10.1182/BLOOD-2019-124978

Montalban-Bravo, G, Kanagal-Shamanna, R, Benton, CB, Class, C, Chien, KS, Sasaki, K, Naqvi, K, Alvarado, Y, Kadia, TM, Ravandi, F, Cortes, JE, Daver, NG, Takahashi, K, DiNardo, CD, Jabbour, E, Borthakur, GM, Pemmaraju, N, Konopleva, MY, Pierce, SA, Bueso-Ramos, CE, Andreeff, M, Patel, KP, Kantarjian, HM & Garcia-Manero, G 2019, 'Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes', Blood, vol. 134. https://doi.org/10.1182/BLOOD-2019-124978

@article{c089efdf58e145e986426f64b0e5bb96,

title = "Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes",

author = "Guillermo Montalban-Bravo and Rashmi Kanagal-Shamanna and Benton, \{Christopher B.\} and Caleb Class and Chien, \{Kelly S.\} and Koji Sasaki and Kiran Naqvi and Yesid Alvarado and Kadia, \{Tapan M.\} and Farhad Ravandi and Cortes, \{Jorge E.\} and Daver, \{Naval G.\} and Koichi Takahashi and DiNardo, \{Courtney D.\} and Elias Jabbour and Borthakur, \{Gautam M.\} and Naveen Pemmaraju and Konopleva, \{Marina Y\} and Pierce, \{Sherry A.\} and Bueso-Ramos, \{Carlos E.\} and Michael Andreeff and Patel, \{Keyur P.\} and Kantarjian, \{Hagop M.\} and Guillermo Garcia-Manero",

note = "INTRODUCTION:TP53 mutations are associated with adverse outcomes and shorter response to hypomethylating agents (HMA) in myelodysplastic syndromes (MDS). There",

year = "2019",

month = nov,

day = "13",

doi = "10.1182/BLOOD-2019-124978",

language = "American English",

volume = "134",

journal = "Blood",

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TY - JOUR

T1 - Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes

AU - Montalban-Bravo, Guillermo

AU - Kanagal-Shamanna, Rashmi

AU - Benton, Christopher B.

AU - Class, Caleb

AU - Chien, Kelly S.

AU - Sasaki, Koji

AU - Naqvi, Kiran

AU - Alvarado, Yesid

AU - Kadia, Tapan M.

AU - Ravandi, Farhad

AU - Cortes, Jorge E.

AU - Daver, Naval G.

AU - Takahashi, Koichi

AU - DiNardo, Courtney D.

AU - Jabbour, Elias

AU - Borthakur, Gautam M.

AU - Pemmaraju, Naveen

AU - Konopleva, Marina Y

AU - Pierce, Sherry A.

AU - Bueso-Ramos, Carlos E.

AU - Andreeff, Michael

AU - Patel, Keyur P.

AU - Kantarjian, Hagop M.

AU - Garcia-Manero, Guillermo

N1 - INTRODUCTION:TP53 mutations are associated with adverse outcomes and shorter response to hypomethylating agents (HMA) in myelodysplastic syndromes (MDS). There

PY - 2019/11/13

Y1 - 2019/11/13

UR - https://ashpublications.org/blood/article/134/Supplement_1/1711/427633/Genomic-Context-and-TP53-Allele-Frequency-Define

U2 - 10.1182/BLOOD-2019-124978

DO - 10.1182/BLOOD-2019-124978

M3 - Article

VL - 134

JO - Blood

JF - Blood

ER -

Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes

Disciplines

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