KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

Yue Wei; Hong Zheng; Naran Bao; Shan Jiang; Carlos E. Bueso-Ramos; Joseph Khoury; Caleb Class; Yue Lu; Kevin Lin; Hui Yang; Irene Ganan-Gomez; Daniel T. Starczynowski; Daniel T. Starczynowski; Kim Anh; Simona Colla; Guillermo Garcia-Manero

doi:10.1182/BLOODADVANCES.2018024166

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

Yue Wei, Hong Zheng, Naran Bao, Shan Jiang, Carlos E. Bueso-Ramos, Joseph Khoury, Caleb Class, Yue Lu, Kevin Lin, Hui Yang, Irene Ganan-Gomez, Daniel T. Starczynowski, Daniel T. Starczynowski, Kim Anh, Simona Colla, Guillermo Garcia-Manero

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Blood Advances
Volume	2
Issue number	19
DOIs	https://doi.org/10.1182/BLOODADVANCES.2018024166
State	Published - Oct 9 2018

Disciplines

Biology
Oncology

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Wei, Y., Zheng, H., Bao, N., Jiang, S., Bueso-Ramos, C. E., Khoury, J., Class, C., Lu, Y., Lin, K., Yang, H., Ganan-Gomez, I., Starczynowski, D. T., Starczynowski, D. T., Anh, K., Colla, S., & Garcia-Manero, G. (2018). KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice. Blood Advances, 2(19). https://doi.org/10.1182/BLOODADVANCES.2018024166

@article{7bc66aa0ae604e77919ea67d51171acb,

title = "KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.",

author = "Yue Wei and Hong Zheng and Naran Bao and Shan Jiang and Bueso-Ramos, {Carlos E.} and Joseph Khoury and Caleb Class and Yue Lu and Kevin Lin and Hui Yang and Irene Ganan-Gomez and Starczynowski, {Daniel T.} and Starczynowski, {Daniel T.} and Kim Anh and Simona Colla and Guillermo Garcia-Manero",

note = "Key Points. Overexpression of KDM6B mediates activation of innate immune signals and has a role in MDS and CMML pathogenesis.KDM6B targeting has therapeutic pot",

year = "2018",

month = oct,

day = "9",

doi = "10.1182/BLOODADVANCES.2018024166",

language = "American English",

volume = "2",

journal = "Blood Advances",

number = "19",

}

TY - JOUR

T1 - KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

AU - Wei, Yue

AU - Zheng, Hong

AU - Bao, Naran

AU - Jiang, Shan

AU - Bueso-Ramos, Carlos E.

AU - Khoury, Joseph

AU - Class, Caleb

AU - Lu, Yue

AU - Lin, Kevin

AU - Yang, Hui

AU - Ganan-Gomez, Irene

AU - Starczynowski, Daniel T.

AU - Anh, Kim

AU - Colla, Simona

AU - Garcia-Manero, Guillermo

N1 - Key Points. Overexpression of KDM6B mediates activation of innate immune signals and has a role in MDS and CMML pathogenesis.KDM6B targeting has therapeutic pot

PY - 2018/10/9

Y1 - 2018/10/9

UR - http://www.bloodadvances.org/content/2/19/2491?sso-checked=true

U2 - 10.1182/BLOODADVANCES.2018024166

DO - 10.1182/BLOODADVANCES.2018024166

M3 - Article

VL - 2

JO - Blood Advances

JF - Blood Advances

IS - 19

ER -

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

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