KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

Yue Wei; Hong Zheng; Naran Bao; Shan Jiang; Carlos E. Bueso-Ramos; Joseph Khoury; Caleb Class; Yue Lu; Kevin Lin; Hui Yang; Irene Ganan-Gomez; Daniel T. Starczynowski; Daniel T. Starczynowski; Kim Anh; Simona Colla; Guillermo Garcia-Manero

doi:10.1182/BLOODADVANCES.2018024166

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

Yue Wei
, Hong Zheng
, Naran Bao
, Shan Jiang
, Carlos E. Bueso-Ramos
, Joseph Khoury
, Caleb Class
, Yue Lu
, Kevin Lin
, Hui Yang
, Irene Ganan-Gomez
, Daniel T. Starczynowski
, Daniel T. Starczynowski
, Kim Anh
, Simona Colla
, Guillermo Garcia-Manero

Department of Leukemia,
Institute for Applied Cancer Science,
Department of Hematopathology,
Department of Biostatistics, and
University of Texas MD Anderson Cancer Center
University of Cincinnati
Cincinnati Children's Hospital Medical Center

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Blood Advances
Volume	2
Issue number	19
DOIs	https://doi.org/10.1182/BLOODADVANCES.2018024166
State	Published - Oct 9 2018

Disciplines

Biology
Oncology

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Wei, Y., Zheng, H., Bao, N., Jiang, S., Bueso-Ramos, C. E., Khoury, J., Class, C., Lu, Y., Lin, K., Yang, H., Ganan-Gomez, I., Starczynowski, D. T., Starczynowski, D. T., Anh, K., Colla, S., & Garcia-Manero, G. (2018). KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice. Blood Advances, 2(19). https://doi.org/10.1182/BLOODADVANCES.2018024166

@article{7bc66aa0ae604e77919ea67d51171acb,

title = "KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.",

author = "Yue Wei and Hong Zheng and Naran Bao and Shan Jiang and Bueso-Ramos, \{Carlos E.\} and Joseph Khoury and Caleb Class and Yue Lu and Kevin Lin and Hui Yang and Irene Ganan-Gomez and Starczynowski, \{Daniel T.\} and Starczynowski, \{Daniel T.\} and Kim Anh and Simona Colla and Guillermo Garcia-Manero",

note = "Key Points. Overexpression of KDM6B mediates activation of innate immune signals and has a role in MDS and CMML pathogenesis.KDM6B targeting has therapeutic pot",

year = "2018",

month = oct,

day = "9",

doi = "10.1182/BLOODADVANCES.2018024166",

language = "American English",

volume = "2",

journal = "Blood Advances",

number = "19",

}

TY - JOUR

T1 - KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

AU - Wei, Yue

AU - Zheng, Hong

AU - Bao, Naran

AU - Jiang, Shan

AU - Bueso-Ramos, Carlos E.

AU - Khoury, Joseph

AU - Class, Caleb

AU - Lu, Yue

AU - Lin, Kevin

AU - Yang, Hui

AU - Ganan-Gomez, Irene

AU - Starczynowski, Daniel T.

AU - Anh, Kim

AU - Colla, Simona

AU - Garcia-Manero, Guillermo

N1 - Key Points. Overexpression of KDM6B mediates activation of innate immune signals and has a role in MDS and CMML pathogenesis.KDM6B targeting has therapeutic pot

PY - 2018/10/9

Y1 - 2018/10/9

UR - http://www.bloodadvances.org/content/2/19/2491?sso-checked=true

U2 - 10.1182/BLOODADVANCES.2018024166

DO - 10.1182/BLOODADVANCES.2018024166

M3 - Article

VL - 2

JO - Blood Advances

JF - Blood Advances

IS - 19

ER -

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.

Disciplines

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