Novel Targeting Approaches of Nanoparticles for Anticancers Drug Delivery: A Focused Review

Yatri S. Patel; Nandita Das; Sudip Das

Novel Targeting Approaches of Nanoparticles for Anticancers Drug Delivery: A Focused Review

Yatri S. Patel
, Nandita Das
, Sudip Das

Butler University

Research output: Contribution to journal › Article › peer-review

Abstract

Nanoparticles have presented a new paradigm in anticancer drug delivery to reduce adverse effects and improve therapeutic outcomes. Nanoparticle surface properties and morphology significantly affect the drug delivery to tumors while passive targeting. Conjugations with hyaluronic acid, transferrin and aptamers have shown to be effective in active targeting of anticancer drugs to tumor tissues. This review presents an overview of some credible techniques of passive and active drug delivery to tumors.

Original language	American English
Journal	Scholarship and Professional Work – COPHS
Volume	5
Issue number	9
State	Published - Sep 1 2019

Keywords

Nanoparticle
aptamer
cancer
hyaluronic acid
targeting
transferrin

Disciplines

Pharmacy and Pharmaceutical Sciences

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Novel Targeting Approaches of Nanoparticles for Anticancers DrugFinal published version, 493 KBLicense: Unspecified

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title = "Novel Targeting Approaches of Nanoparticles for Anticancers Drug Delivery: A Focused Review",

abstract = " Nanoparticles have presented a new paradigm in anticancer drug delivery to reduce adverse effects and improve therapeutic outcomes. Nanoparticle surface properties and morphology significantly affect the drug delivery to tumors while passive targeting. Conjugations with hyaluronic acid, transferrin and aptamers have shown to be effective in active targeting of anticancer drugs to tumor tissues. This review presents an overview of some credible techniques of passive and active drug delivery to tumors.",

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AU - Patel, Yatri S.

AU - Das, Nandita

AU - Das, Sudip

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Y1 - 2019/9/1

N2 - Nanoparticles have presented a new paradigm in anticancer drug delivery to reduce adverse effects and improve therapeutic outcomes. Nanoparticle surface properties and morphology significantly affect the drug delivery to tumors while passive targeting. Conjugations with hyaluronic acid, transferrin and aptamers have shown to be effective in active targeting of anticancer drugs to tumor tissues. This review presents an overview of some credible techniques of passive and active drug delivery to tumors.

AB - Nanoparticles have presented a new paradigm in anticancer drug delivery to reduce adverse effects and improve therapeutic outcomes. Nanoparticle surface properties and morphology significantly affect the drug delivery to tumors while passive targeting. Conjugations with hyaluronic acid, transferrin and aptamers have shown to be effective in active targeting of anticancer drugs to tumor tissues. This review presents an overview of some credible techniques of passive and active drug delivery to tumors.

KW - Nanoparticle

KW - aptamer

KW - cancer

KW - hyaluronic acid

KW - targeting

KW - transferrin

UR - https://digitalcommons.butler.edu/cophs_papers/254

M3 - Article

VL - 5

JO - Scholarship and Professional Work – COPHS

JF - Scholarship and Professional Work – COPHS

IS - 9

ER -

Novel Targeting Approaches of Nanoparticles for Anticancers Drug Delivery: A Focused Review

Abstract

Keywords

Disciplines

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