Taste, Olfactory and Trigeminal Neophobia in Rats with Forebrain Lesions

Jian-You Lin; Christopher T. Roman; Justin St. Andre; Steve Reilly

doi:10.1016/j.brainres.2008.11.040

Taste, Olfactory and Trigeminal Neophobia in Rats with Forebrain Lesions

Jian-You Lin, Christopher T. Roman, Justin St. Andre, Steve Reilly

Research output: Contribution to journal › Article › peer-review

Abstract

The present study was designed to examine whether lesions of the insular cortex (IC; Experiment 1), the basolateral amygdala (BLA) or medial amygdala (MeA; Experiment 2) influence the neophobic reactions to orally consumed liquid stimuli. Three different types of stimuli were used: taste (0.5% saccharin), olfactory (0.1% amyl acetate), and trigeminal (0.01 mM capsaicin). Rats with IC, BLA and MeA lesions showed normal responses to the olfactory and trigeminal stimuli. Each type of lesion, however, disrupted the initial occurrence of neophobia to the taste stimulus. The significance of these findings to conditioned taste aversion is discussed.

Original language	American English
Journal	Scholarship and Professional Work – COPHS
Volume	1251
DOIs	https://doi.org/10.1016/j.brainres.2008.11.040
State	Published - Jan 1 2009

Keywords

Amygdala
insular cortex
neophobia
rat

Disciplines

Behavioral Neurobiology
Neuroscience and Neurobiology

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title = "Taste, Olfactory and Trigeminal Neophobia in Rats with Forebrain Lesions",

abstract = " The present study was designed to examine whether lesions of the insular cortex (IC; Experiment 1), the basolateral amygdala (BLA) or medial amygdala (MeA; Experiment 2) influence the neophobic reactions to orally consumed liquid stimuli. Three different types of stimuli were used: taste (0.5\% saccharin), olfactory (0.1\% amyl acetate), and trigeminal (0.01 mM capsaicin). Rats with IC, BLA and MeA lesions showed normal responses to the olfactory and trigeminal stimuli. Each type of lesion, however, disrupted the initial occurrence of neophobia to the taste stimulus. The significance of these findings to conditioned taste aversion is discussed.",

keywords = "Amygdala, insular cortex, neophobia, rat",

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language = "American English",

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T1 - Taste, Olfactory and Trigeminal Neophobia in Rats with Forebrain Lesions

AU - Lin, Jian-You

AU - Roman, Christopher T.

AU - St. Andre, Justin

AU - Reilly, Steve

PY - 2009/1/1

Y1 - 2009/1/1

N2 - The present study was designed to examine whether lesions of the insular cortex (IC; Experiment 1), the basolateral amygdala (BLA) or medial amygdala (MeA; Experiment 2) influence the neophobic reactions to orally consumed liquid stimuli. Three different types of stimuli were used: taste (0.5% saccharin), olfactory (0.1% amyl acetate), and trigeminal (0.01 mM capsaicin). Rats with IC, BLA and MeA lesions showed normal responses to the olfactory and trigeminal stimuli. Each type of lesion, however, disrupted the initial occurrence of neophobia to the taste stimulus. The significance of these findings to conditioned taste aversion is discussed.

AB - The present study was designed to examine whether lesions of the insular cortex (IC; Experiment 1), the basolateral amygdala (BLA) or medial amygdala (MeA; Experiment 2) influence the neophobic reactions to orally consumed liquid stimuli. Three different types of stimuli were used: taste (0.5% saccharin), olfactory (0.1% amyl acetate), and trigeminal (0.01 mM capsaicin). Rats with IC, BLA and MeA lesions showed normal responses to the olfactory and trigeminal stimuli. Each type of lesion, however, disrupted the initial occurrence of neophobia to the taste stimulus. The significance of these findings to conditioned taste aversion is discussed.

KW - Amygdala

KW - insular cortex

KW - neophobia

KW - rat

UR - https://digitalcommons.butler.edu/cophs_papers/168

U2 - 10.1016/j.brainres.2008.11.040

DO - 10.1016/j.brainres.2008.11.040

M3 - Article

VL - 1251

JO - Scholarship and Professional Work – COPHS

JF - Scholarship and Professional Work – COPHS

ER -

Taste, Olfactory and Trigeminal Neophobia in Rats with Forebrain Lesions

Abstract

Keywords

Disciplines

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