Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia

Guillermo Montalban-Bravo; Faezeh Darbaniyan; Rashmi Kanagal-Shamanna; Irene Ganan-Gomez; Caleb A. Class; Caleb A. Class; Koji Sasaki; Kiran Naqvi; Yue Wei; Hui Yang; Kelly A. Soltysiak; Kelly S. Chien; Carlos Bueso-Ramos; Kim-Anh Do; Hagop Kantarjian; Guillermo Garcia-Manero

doi:10.1016/J.LEUKRES.2021.106511

Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia

Guillermo Montalban-Bravo, Faezeh Darbaniyan, Rashmi Kanagal-Shamanna, Irene Ganan-Gomez, Caleb A. Class, Caleb A. Class, Koji Sasaki, Kiran Naqvi, Yue Wei, Hui Yang, Kelly A. Soltysiak, Kelly S. Chien, Carlos Bueso-Ramos, Kim-Anh Do, Hagop Kantarjian, Guillermo Garcia-Manero

University of Texas MD Anderson Cancer Center

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Leukemia Research
DOIs	https://doi.org/10.1016/J.LEUKRES.2021.106511
State	Published - Jan 19 2021

Disciplines

Biology
Oncology

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Montalban-Bravo, G., Darbaniyan, F., Kanagal-Shamanna, R., Ganan-Gomez, I., Class, C. A., Class, C. A., Sasaki, K., Naqvi, K., Wei, Y., Yang, H., Soltysiak, K. A., Chien, K. S., Bueso-Ramos, C., Do, K.-A., Kantarjian, H., & Garcia-Manero, G. (2021). Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia. Leukemia Research. https://doi.org/10.1016/J.LEUKRES.2021.106511

Montalban-Bravo, G, Darbaniyan, F, Kanagal-Shamanna, R, Ganan-Gomez, I, Class, CA , Class, CA, Sasaki, K, Naqvi, K, Wei, Y, Yang, H, Soltysiak, KA, Chien, KS, Bueso-Ramos, C, Do, K-A, Kantarjian, H & Garcia-Manero, G 2021, 'Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia', Leukemia Research. https://doi.org/10.1016/J.LEUKRES.2021.106511

@article{bcd4a4b181824a03adf4bd4f60c792fa,

title = "Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia",

author = "Guillermo Montalban-Bravo and Faezeh Darbaniyan and Rashmi Kanagal-Shamanna and Irene Ganan-Gomez and Class, {Caleb A.} and Class, {Caleb A.} and Koji Sasaki and Kiran Naqvi and Yue Wei and Hui Yang and Soltysiak, {Kelly A.} and Chien, {Kelly S.} and Carlos Bueso-Ramos and Kim-Anh Do and Hagop Kantarjian and Guillermo Garcia-Manero",

note = "Bone marrow cells from healthy individuals and 19 patients with CMML were compared. * Top upregulated genes included IFN alpha and beta signaling. * 23 genes involved in regulation of monopoiesis were upregulated in CMML patients. * 3 monopoiesis regulation genes differentiated patients into two prognostic subsets.",

year = "2021",

month = jan,

day = "19",

doi = "10.1016/J.LEUKRES.2021.106511",

language = "American English",

journal = "Leukemia Research",

}

TY - JOUR

T1 - Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia

AU - Montalban-Bravo, Guillermo

AU - Darbaniyan, Faezeh

AU - Kanagal-Shamanna, Rashmi

AU - Ganan-Gomez, Irene

AU - Class, Caleb A.

AU - Sasaki, Koji

AU - Naqvi, Kiran

AU - Wei, Yue

AU - Yang, Hui

AU - Soltysiak, Kelly A.

AU - Chien, Kelly S.

AU - Bueso-Ramos, Carlos

AU - Do, Kim-Anh

AU - Kantarjian, Hagop

AU - Garcia-Manero, Guillermo

N1 - Bone marrow cells from healthy individuals and 19 patients with CMML were compared. * Top upregulated genes included IFN alpha and beta signaling. * 23 genes involved in regulation of monopoiesis were upregulated in CMML patients. * 3 monopoiesis regulation genes differentiated patients into two prognostic subsets.

PY - 2021/1/19

Y1 - 2021/1/19

UR - https://www.sciencedirect.com/science/article/abs/pii/S0145212621000126

U2 - 10.1016/J.LEUKRES.2021.106511

DO - 10.1016/J.LEUKRES.2021.106511

M3 - Article

JO - Leukemia Research

JF - Leukemia Research

ER -

Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia

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